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DeCS
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Descriptor Inglés:
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Checkpoint Kinase 1
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Descriptor Español:
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Quinasa 1 Reguladora del Ciclo Celular (Checkpoint 1)
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Descriptor Portugués:
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Quinase 1 do Ponto de Checagem
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Sinónimos Inglés:
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Checkpoint-1 Kinase
Chk1 Kinase
Chk1 Protein Kinase
Protein Kinase, Chk1
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Categoría:
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D08.811.913.696.620.682.700.143
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Definición Inglés:
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A serine/threonine-specific protein kinase which is encoded by the CHEK1 gene in humans. Checkpoint kinase 1 (also known as Chk1) coordinates DNA damage response and cell cycle checkpoint response. Under these conditions, activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death, to prevent damaged cells from progressing through the cell cycle. |
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Nota Histórica Inglés:
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2017 (2004)
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Calificadores Permitidos Inglés:
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Número del Registro:
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56510
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Identificador Único:
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D000071877
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Ocurrencia en la BVS:
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Similar:
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DeCS
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